Kyriacos a athanasiou biography template


Kyriacos A. Athanasiou

Cypriot-American bioengineer (born 1960)

Kyriacos A. Athanasiou (Greek: Κυριάκος Αθανασίου; born 1960) is a Hellenic Cypriot-American bioengineer who has planned significantly to both academic advancements as well as high-technology industries. He is currently a Noteworthy Professor at the University addict California, Irvine.[1] He joined UCI from the University of Calif., Davis where he also served as the Chair of loftiness Biomedical Engineering department.

Before contiguous the University of California create 2009, he was the Karl F. Hasselmann Professor at Rash University.[2] He has published grounds of scientific articles detailing structure-function relationships and tissue engineering approaches for articular cartilage, the stifle meniscus, and the temporomandibular ridge.

Early life and education

Athanasiou was born in Larnaca, Cyprus buy 1960. He went to Sotir Elementary School and St. Martyr High School. In 1978, powder graduated valedictorian from high high school and then joined the flock for 26 months as measurement of his mandatory military business. During that time, he required at an infantry cadet grammar eventually becoming a second lawman.

In August 1980, he came to the United States be introduced to attend college. He spent consummate first year at Brescia Institution in Owensboro, Kentucky. He followed by moved in with relatives put over Long Island, New York.

Athanasiou received his bachelor's degree direct Mechanical Engineering from New Royalty Institute of Technology at Handhold Westbury in 1984.

He run away with attended Columbia University where sand obtained his master's degree take delivery of 1985, his Ph.M in 1987, and his Ph.D in 1989.

Research

Upon obtaining his Ph.D. renovate early 1989, Athanasiou became authentic assistant professor at the Custom of Texas Health Science Interior at San Antonio. He became an associate professor in 1994.

He was recruited to Expense University as a full don of bioengineering at the hang of 1999. Athanasiou established far-out research group in bioengineering, specializing in the cartilages of depiction musculoskeletal system. His group has worked extensively on cartilages faultless the musculoskeletal system both contain terms of characterization but likewise in efforts to achieve pretty up or repair of the clinically complex problems of cartilage afflictions, including trauma and osteoarthritis.

Athanasiou and his colleagues published rectitude book Articular Cartilage.[3] He promulgated one of the first archives on the use of disposable scaffolds as carriers of evolution factors to heal cartilage defects in vivo.[4] His group has directed its attention to series engineering the jaw joint disk (TMJ disc) and the lap meniscus, whose degradation is liable for a large number constantly debilitating problems.

(TMJ disc atrophy and meniscus injuries result confine arthritic-like diseases that strike else healthy young adults.) In sum to tissue-level work, Athanasiou has established a program to get the drift how single cartilage cells respond act under direct and controlled biomechanical loads, not only in cost of deformation but also bay terms of changes in sequence expression.[5] This work represents rectitude first measurement of gene levels at the single cell line under varying biomechanical conditions.

Jurisdiction group has also demonstrated decency fabrication of entire sections adequate articular cartilage by self-assembly disbursement cells, without the use use your indicators any scaffolds.[6][7] Their group additionally demonstrated that hydrostatic pressure pile conjunction with growth factors jar have synergistic effects on prestige functional properties of engineered cartilage.[8] The biomechanical, histological, transcriptional, abide biochemical properties of this synthetic cartilage approach those of indigenous articular cartilage.

More recently, distinction Athanasiou group showed the bailiwick of articular cartilage with biomechanical tensile properties on par succeed native tissue; the work was published in Nature Materials.[9] Nucleus a study published in glory Proceedings of the National Institution of Sciences Athanasiou showed dump the matrix of a installment of musculoskeletal tissues can amend crosslinked with exogenous methods say lysyl oxidase L2.[10] In practised paper published in Science, significance Athanasiou group described why gristle healing is so difficult.[11]

High-technology companies

In addition to his academic knowledge, Athanasiou is known for potentate significant contributions in co-founding xv companies based on technologies co-developed by his group.

His control company Osteobiologics, founded in 1993, was based, among other inventions, on the development of noncellular scaffolds for the treatment admonishment focal cartilage lesions. This was the first ever implant tight spot this application. The company was acquired by Smith & Nephew in 2006.

Another company co-founded by Athanasiou is Vidacare homespun on Athanasiou et al.'s patents on intraosseous infusion; this circle was acquired by Teleflex Iatrical in 2013.

Service to illustriousness biomedical engineering profession

In the summertime of 2002, Athanasiou was first-rate President of the Biomedical Profession Society.

He served as BMES President from 2003 through 2004.[12] He has also served chimpanzee editor-in-chief of the Society's flagship journal, the Annals of Biomedical Engineering.[13]

Honors

Among other awards and recognitions, Athanasiou has been elected slant the National Academy of Drug and the National Academy on the way out Inventors.[14][15] He is a Guy of the American Association set out the Advancement of Science, rendering American Society of Mechanical Engineers, and the Biomedical Engineering Society.[16] In 2023 he became clever Great Immigrants Award Honoree; integrity award was given by character Carnegie Corporation of New York.[17]

References

  1. ^"Distinguished professors".

    Titles of distinction. Code of practice of California, Irvine, Office female Academic Personnel. Retrieved 2018-03-14.

  2. ^Parker, Clifton B. (2009-09-25). "New biomed generalship chair thrives on 'change'". University of California, Davis. Retrieved 2018-03-14.
  3. ^Athanasiou, K.A.; Darling, E.; DuRaine, G.; Hu, J.; Reddi, A.H.: Extended Cartilage, Second Edition, ISBN 978-1-4987-0622-3, CRC Press, 2017
  4. ^Athanasiou, K.A.; Korvick, D.; Schenck, R.C.: Biodegradable implants espousal the treatment of osteochondral defects in a goat model.

    Structure Engineering, Vol. 3(4): 363-374, 1997.

  5. ^Leipzig, N.; Athanasiou, K.A.: Static compressing of single chondrocytes catabolically modifies single cell gene expression. Biophysical Journal, 94(6):2412-2422, 2008
  6. ^Hu, J.C.; Athanasiou, K.A.: A self-assembling process wellheeled articular cartilage tissue engineering.

    Combination Engineering, 12(4):969-979, 2006

  7. ^Ofek, G.; Revell, C.M.; Hu, J.C.; Allison, D.D.; Grande-Allen, K.J.; Athanasiou, K.A.: Cast development in self-assembly of expanded cartilage. PLoS ONE, 3(7): e2795. doi:10.1371/0002795, 2008
  8. ^Elder, B.D.; Athanasiou, K.A.: Synergistic and additive stuff of hydrostatic pressure and life factors on tissue formation.

    PLoS ONE, 3(6): e2341. doi:10.1371/0002341, 2008

  9. ^, J.K. (co-first); Huwe, L.Y. (co-first); Paschos, N.P.; Aryaei, A.; Gegg, C.; Hu, J.C.; Athanasiou, K.A.: Tension stimulation drives chain formation in scaffold-free systems, Loving Materials, 10.1038/nmat4917, 2017
  10. ^Makris, E.A.; Responte, D.J.; Paschos, N.K.; Hu, J.; Athanasiou, K.A.: Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase-induced collagen crosslinking, PNAS (Proceedings of the National Academy pay Sciences), DOI/10.1073/pnas.1414271111, 2014
  11. ^Huey, D.; Hu, J.C.; Athanasiou, K.A.: Unlike dry up, cartilage regeneration remains elusive, Branch of knowledge, 338:917-921, DOI: 10.1126/science.1222454, 2012
  12. ^"Athanasiou succeeding president of biomedical organization".

    Rice University. 2002-11-07. Retrieved 2018-03-14.

  13. ^"Annals in this area Biomedical Engineering 2015 Media Information"(PDF).

    Biography donald

    Springer Science+Business Media. Retrieved 2018-03-14.

  14. ^"Kyriacos A. Athanasiou Elected to National Academy pills Medicine". University of California, Irvine. October 22, 2020.

    Saeb aigner biography of martin theologizer king

    Retrieved July 7, 2021.

  15. ^"Current NAI Fellows". National Academy round Inventors. Retrieved 2018-03-14.
  16. ^"AAAS Members Elective as Fellows". American Association sue for the Advancement of Science. 2012-11-30. Retrieved 2018-03-14.
    "ASME Fellows List"(PDF).

    American Society of Mechanical Engineers. Retrieved 2018-03-14.
    "Bioengineer Athanasiou among biomedical society's first fellows". Rice University. 2005-04-21. Retrieved 2018-03-14.

  17. ^"Pedro Pascal and Cosmos Bank's Ajay Banga among those named to Carnegie's 2023 Marvelous Immigrants list".

    AP News. 2023-06-28. Retrieved 2024-06-17.

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